Laboratory for Genetic Epidemiology


http://www.genepi.org.au

Dr Kylie Hewitt

Kylie Hewitt

Kylie graduated from Monash University with a Bachelor of Science Degree with Honours in Immunology. Kylie then went onto to complete a PhD, under the supervision of Professor Evan Simpson investigating the roles that the hormone estrogen has in metabolic pathways and obesity. Kylie then moved to UK with a Leverhulme Visiting fellowship to work under Profeesor Paul Stewart at the University of Birmingham on projects involved in stress hormones and metabolic pathways. Kylie moved from the Leverhulme trust fellowship to a Wellcome Trust program grant funding for the remaining two years.

Kylie has now joined the Genetic Epidemiology Laboratory at the Western Australia Institute of Medical Research, Perth Australia as a Study Coordinator for the Genetic Understanding of Asbestos-Related Disorders (GURAD) project in collaboration with the National Centre for Asbestos-Related Disorders (NCARD).

Qualifications

1998BSc (Hons) - Immunology, Monash University, Australia
2003PhD - Biochemistry and Molecular Biology, Monash University, Australia
Thesis Title: "The liver phenotype of the aromatase knockout (ArKO) mouse"

Awards and Honours

2000-2003Travel awards from the Endocrine Society of Australia to attend Society Meetings
2001Faculty of Medicine, Nursing and Health Sciences, Monash University, Australia Serotec award for Best Poster Presentation
2002Women in Endocrinology, USA Society, Travel Award to attend the American Endocrine Meeting
2002Women in Endocrinology, Australasian Society, Novo Noradisk Travel Award to attend the American Endocrine Meeting
2004-2005Leverhulme Trust Fellowship
2005-2007Travel Awards from The British Society of Endocrinology to attend the British Endocrine Society meetings
2005-2006Travel Awards from The British Society of Endocrinology to attend the American Endocrine meetings
2005-2006Divisional Funding to attend the American Endocrine Society meetings
2007Awarded Small Project Grant for an Independent Research Project, £4000
2007British Endocrine Society, Best poster prize, Birmingham
2007Keystone Conference, Metabolic Syndrome and Cardiovascular Disease, Steamboat Springs, Pfizer Scholarship

Publications

  1. Hewitt K, Walker E, Stewart P. Minireview: Hexose-6-Phosphate Dehydrogenase and Redox Control of 11{beta}-Hydroxysteroid Dehydrogenase Type 1 Activity. Endocrinology. 2005 Jun;146(6):2539-43.
  2. Simpson E, Misso M, Hewitt K, Hill R, Boon WC, Jones M, Kovacic A, Zhou J, Clyne CD. Estrogen--the Good, the Bad, and the Unexpected. Endocr Rev. 2005 May;26(3):322-330.
  3. Simpson E, Jones M, Misso M, Hewitt K, Hill R, Maffei L, Carani C, Boon WC. Estrogen, a fundamental player in energy homeostasis. J Steroid Biochem Mol Biol. 2005 May;95(1-5):3-8.
  4. Misso M, Hewitt K, Boon WC, Murata Y, Jones M, Simpson E. Cholesterol feeding prevents adiposity in the obese female aromatase knockout (ArKO) mouse. Horm Metab Res. 2005 Jan;37(1):26-31.
  5. Hewitt K, Pratis K, Jones M, Simpson E. Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse. Endocrinology. 2004 Apr;145(4):1842-8.
  6. Hewitt K, Boon WC, Murata Y, Jones M, Simpson E. The aromatase knockout (ArKO) mouse presents with a sexually dimorphic disruption to cholesterol homeostasis. Endocrinology, 2003, 144(9):3895-3903.
  7. Jones M, Thornburn AW, Britt KL, Hewitt KN, Wreford NG, Proietto J, Oz O, Leury B, Robertson K, Simpson ER. Aromatase deficient (ArKO) mice have a phenotype of increased adiposity. (2001) The Journal of Steroid Biochemistry and Molecular Biology: 79: 3-9.
  8. Jones M, Thornburn AW, Britt KL, Hewitt KN, Wreford NG, Proietto J, Oz O, Leury B, Robertson K, Simpson ER. Aromatase deficient (ArKO) mice have a phenotype of increased adiposity. (2000) Proc. Natl. Acad. Sci. USA 97: 12735-12740.